One of the most bloodsheding pandemics in human history that wiped out 50% of the entire population of Europe. It first was in 1346 AD to 1353 AD. It killed up to 75 to 200 MILLION people in Europe. It all started from a disease caused by Yersinia Pestis. Basically it first started in Sicily,Italy spreading the disease up north. The Black Death originated in Silk Road,Crimea. From there it was most likely carrying rat fleas which caused the disease. The aftermath took Europe to get its population recovered for 150 years. May all of those infected rest in peace.